Novel Targeted Combinations in CNS Lymphoma

By Greg Nowakowski, MD, Christian Grommes, MD, Avyakta Kallam, MD, Katherine Peters, MD, PhD - Last Updated: January 21, 2025

Grzegorz Nowakowski, MD, of the Mayo Clinic, moderated a discussion on central nervous system (CNS) lymphoma with an expert panel featuring Christian Grommes, MD, of the Memorial Sloan Kettering Cancer Center; Katherine Peters, MD, PhD, of the Preston Robert Tisch Brain Tumor Center; and Avyakta Kallam, MD, of the City of Hope Comprehensive Cancer Center.

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In this segment, the experts discussed novel targeted combinations in CNS lymphoma, including Bruton tyrosine kinase (BTK) inhibitors in combination with interleukin-1 receptor-associated kinase (IRAK) inhibitors and BTK inhibitors in combination with chemotherapy.

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