The European Commission (EC) has granted full Marketing Authorization to luspatercept for the treatment of anemia in adult patients with nontransfusion-dependent beta thalassemia. The centralized Marketing Authorization approves use of luspatercept in all European Union (EU) member states, as well as Norway, Iceland, and Liechtenstein. ...
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The approval of the treatment provides patients with an alternative to a product that has historically been in shortage.
Drs. Kambhampati and Thiruvengadam discuss their study investigating the cost effectiveness of pola-R-CHP in DLBCL.
The 60-day mortality rate was around twice as high in patients with KMT2A rearrangement.
While NPM1 mutations impacted CR rates, they had “no impact” on RFS and OS after each line of salvage therapy.
Axicabtagene ciloleucel showed a significant improvement in OS over standard of care in relapsed or refractory LBCL.
Novel therapies and “game-changing drugs” have made a major impact on the treatment of myeloma, Dr. Wong said.
Patients with clinical progression had a significantly shorter median OS from their first relapse.
Revumenib is a potent, selective oral inhibitor of interaction between menin and KMT2A.
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