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Mark Sorial, PharmD, BCOP, shared the latest research from the Salvia Jain Lab's PETAL Consortium. Bexobrutideg, an orally bioavailable, brain-penetrant BTK degrader, is being evaluated in a phase 1a/b study. This agent which has newly received an ODD for MDS recalibrates the immune system to attack hematological and solid tumors. Machine learning may aid point-of-care clinical decision-making for NHL patients receiving CAR T-cell therapy. Some major themes for practice include identifying patients at risk for early progression and emphasis on quality of life.