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Follicular Lymphoma
The latest news, research, and perspectives in follicular lymphoma (FL).
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What Are the Survival Outcomes of Transformed Follicular Lymphoma After CAR-T?
Melissa Badamo
Follicular Lymphoma
|
November 27, 2024
CD19-directed CAR-T therapy led to improved survival in patients with transformed follicular lymphoma.
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Dr. Luminari Remarks on EU Approval of Odronextamab for DLBCL, Follicular Lymphoma
Stefano Luminari, MD
Aggressive B-Cell Lymphoma
|
October 3, 2024
The positive safety profile of this bispecific antibody makes it well-suited for combination with other treatments.
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European Commission Approves Odronextamab for Follicular Lymphoma, DLBCL
Melissa Badamo
Follicular Lymphoma
|
August 26, 2024
The approval is based on results from the phase I ELM-1 and phase II ELM-2 trials.
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EC Grants Conditional Approval to Epcoritamab for Relapsed or Refractory Follicular Lymphoma
Andrew Moreno
Follicular Lymphoma
|
August 20, 2024
The conditional marketing authorization was given for use as monotherapy in adults after two or more lines of prior therapy.
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Tisagenlecleucel Effective, Safe in Relapsed or Refractory Follicular Lymphoma
Andrew Moreno
Transplantation & Cellular Therapy
|
July 18, 2024
A phase II trial found antitumor effect across patient subgroups and independently of risk factors for disease progression.
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Liso-Cel Shows Promise for Second-Line, Later Management of Follicular Lymphoma
Patrick Daly
Follicular Lymphoma
|
October 4, 2024
Treatment with liso-cel was effective and safe in patients with relapsed or refractory follicular lymphoma in TRANSCEND FL.
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ELARA Trial Update: Tisa-Cel Continues to Show Efficacy, Safety in Follicular Lymphoma
Melissa Badamo
Follicular Lymphoma
|
June 3, 2024
The median progression-free survival, duration of response, and overall survival were not reached.
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Minimized MRD Positivity in Follicular Lymphoma Linked to Long-term Disease Control
Andrew Moreno
Follicular Lymphoma
|
June 3, 2024
MRD is closely associated with disease control success during and after induction therapy in FL, trial analysis finds.
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Liso-Cel Receives Accelerated Approval for Relapsed or Refractory Follicular Lymphoma
Patrick Daly
Follicular Lymphoma
|
August 23, 2024
The US FDA has granted accelerated approval for liso-cel in adult patients with relapsed or refractory follicular lymphoma.
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Study Identifies Features that Predict Follicular Lymphoma Early Relapse
Patrick Daly
Follicular Lymphoma
|
April 9, 2024
Tumor cells in high-risk follicular lymphoma had enhanced B-cell receptor signaling and distinct follicular growth patterns.
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FDA Declines BLA for Odronextamab for Non-Hodgkin Lymphoma
Melissa Badamo
Aggressive B-Cell Lymphoma
|
May 21, 2024
The approval was declined due to the enrollment status of the confirmatory trials.
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FDA Approves Zanubrutinib Plus Obinutuzumab for Relapsed or Refractory Follicular Lymphoma
Patrick Daly
Follicular Lymphoma
|
March 7, 2024
Common adverse reactions to zanubrutinib observed across studies included decreased neutrophil and platelet counts.
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External Comparator Analysis Supports Long-term Value of Axi-Cel in Follicular Lymphoma
Patrick Daly
Follicular Lymphoma
|
March 7, 2024
Axi-cel yielded improved long-term outcomes versus conventional treatments in extended follow-up of the ZUMA-5 trial.
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Liso-Cel ‘Favorable’ Safety Profile in Second-line Follicular Lymphoma
Melissa Badamo
Follicular Lymphoma
|
February 16, 2024
At a median follow-up of 18.1 months, the ORR and CR rates were both 95.7% following liso-cel treatment.
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Dr. Coombs Spotlights Recent CHIP Updates
Chadi Nabhan, MD, MBA, FACP
The HemOnc Pulse
|
February 15, 2024
In episode four of the 2024 season, Dr. Coombs shares updates in CHIP from ASH 2023.
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Expanded Indications for Liso-Cel Under Review in US, Japan
Patrick Daly
Mantle Cell Lymphoma
|
April 2, 2024
Liso-cel received regulatory acceptances from the US FDA and the Ministry of Health, Labour and Welfare in Japan for FL.
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FDA Requests Boxed Warning Label on CAR-T Therapies Used to Treat Blood Cancers
Leah Sherwood
Myeloma
|
February 2, 2024
The agency's statement follows potential risks identified by the FDA Adverse Event Reporting System.
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Epcoritamab Produces Promising Responses in Patients With Follicular Lymphoma
Patrick Daly
Follicular Lymphoma
|
February 20, 2024
Epcoritamab yielded deep responses with promising response rates in high-risk relapsed or refractory follicular lymphoma.
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Dual Treatment Shows Promising Efficacy in Untreated Follicular Lymphoma
Melissa Badamo
Indolent B-Cell Lymphoma
|
February 2, 2024
The trial studied a fixed-duration regimen of mosunetuzumab plus lenalidomide in follicular lymphoma.
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Phase II Study: Mosunetuzumab Shows ‘Highly Encouraging Efficacy’ in Follicular Lymphoma
Melissa Badamo
Indolent B-Cell Lymphoma
|
February 14, 2024
Among 26 response-evaluable patients, the best overall response rate was 96% and the complete response rate was 81%.
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Editorial Board
Sagar Lonial, MD, FACP
Editor-in-Chief | Chief Medical Officer of Winship Cancer Institute at Emory University School of Medicine
Guillermo Garcia-Manero, MD
Associate Editor | Chief, Section of Myelodysplastic Syndromes, The University of Texas MD Anderson Cancer Center
Elias Jabbour, MD
Executive Editor | DB Lane Cancer Research Fund Distinguished Professor in Leukemia Research, MD Anderson Cancer Center
Kami Maddocks, MD
Associate Editor | Professor of Clinical Internal Medicine in the Division of Hematology at The Ohio State University
Thomas Martin, MD
Associate Editor | Clinical Research Director, UCSF Helen Diller Family Comprehensive Cancer Center
Jerald Radich, MD
Associate Editor | Professor in the Clinical Research Division and Kurt Enslein Endowed Chair at Fred Hutch
Laurie Sehn, MD, MPH
Associate Editor | Clinical Professor of Medical Oncology, British Columbia Cancer Centre for Lymphoid Cancer