Study Identifies Dietary Risk Factors for Myeloma

Francesca Castro, MS, RDN, CDN, a Clinical Research Dietitian Nutritionist at the Memorial Sloan Kettering Cancer Center, discussed her study, “Pre-diagnosis Dietary Patterns and Risk of Multiple Myeloma in the NIH-AARP Diet and Health Study.”

The study evaluated the healthy eating index, which compares an individual’s intake with how well they are meeting the US Department of Agriculture dietary guidelines; the alternate Mediterranean diet (aMED) score, which compares intake with the Mediterranean diet score; and the plant-based dietary index, which evaluates vegetarian and vegan diets.

The healthy plant-based dietary index gives a higher positive score to healthy plant foods such as beans, fruits, vegetables, vegetable oils, tea, and coffee, while giving a reverse score to animal intake and unhealthy plant-based foods such as highly saturated fat-based foods, sweets, and sugar-sweetened beverages. A higher score reflects a higher-quality diet.

The researchers removed possible confounders and adjusted for age, body mass index, education, and gender. After adjustment, the healthy plant-based dietary index had a “significant” association with reduced myeloma risk, while the healthy eating index and aMED were not significantly associated with myeloma risk.

Castro attributes these findings to the increased fiber intake found in a plant-based diet.

“Plant-based diets are higher in fiber and phytonutrients,” she emphasized. “There’s a huge fiber gap in the population, specifically in the American population.”

Finally, Castro described the importance of the study. “I think it’s very helpful for patients to know that diet does play a role in overall cancer risk and myeloma risk. Even if they potentially move a little bit in the right direction, it can make a difference in outcomes,” she concluded.