The phase Ib clinical trial is being launched by Cellenkos in partnership with Incyte as part of their LIMBER initiative. Long-term results from the RESPONSE-2 trial confirm efficacy of ruxolitinib for PV. The REFINE trial observed clinically meaningful splenic responses with navitoclax plus ruxolitinib. This phase II study enrolled 34 adult patients with intermediate- to high-risk myelofibrosis.