Should interim PET scans still guide Hodgkin lymphoma treatment? Experts debate imaging, SUV changes and biopsy use in HL. At 5 years, 33% of patients with myeloma receiving cilta-cel in the CARTITUDE-1 trial are alive and disease free. Experts discuss T-cell lymphoma care, new therapies, transplant timing, and the role of NGS in treatment decisions. The phase 3 SURPASS-ET trial presented at ASCO evaluated ropeginterferon alfa-2b versus anagrelide for the treatment of ET. Expert insights from a HemOnc Pulse Live! session offer a compelling look at where CML and MPN care is headed. How have TKIs transformed CML survival and what’s next for treatment-free remission and deeper MPN responses?
Dr. Andorsky discusses CML dose escalation, treatment discontinuation, and unmet needs in leukemia care. 100% MRD-negative CR in Ph+ ALL? Dr. Catherine Lai recaps standout abstracts from an ASCO rapid oral session. Dr. Tam reviews 5-year data from SEQUOIA showing strong efficacy of zanubrutinib in older CLL patients with 17p deletion. Dr. Frederick Locke discussed the ZUMA-7 trial of axi-cel versus standard of care for patients with relapsed/refractory LBCL. Experts debate frontline CLL therapy—time-limited combos vs long-term BTKi—and the role of MRD in treatment decisions. Ryan Jacobs, MD discusses 2025 CLL treatment advances, including BTK/BCL-2 combos, resistance, and time-defined strategies.
Charles Gaulin, MBBS, discussed the future of lymphoma treatment, including the development of novel cellular therapies. Naval Daver, MD, discusses the latest advancements in the treatment of myelodysplastic syndromes Charles Gaulin, MBBS, discussed the safety and efficacy of CD19 CAR-T cell therapy for transformed indolent lymphoma. Kelly Chien, MD, discusses how disparities in access to care, resources, and molecular testing impact outcomes in AML. Anderw Brunner, MD addresses current gaps in MDS research and clinical practice and more. Nirav Shah, MD, MSHP, tells BCT about his team's phase I/II clinical trial findings. Sairah Ahmed, MD, tells about current management challenges and promising developments in treatment options. Seta Degann, MD, resident physician at George Washington University, described the challenges of diagnosing younger patients.