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Nichole Tucker
Articles by Nichole Tucker
Differences in Ide-cel and Cilta-cel Outcomes Call for Personalized RRMM Treatment
Nichole Tucker
Myeloma
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March 10, 2025
BCMA–directed CAR Ts were a vital advancement to RRMM treatment. Now, oncologists wonder which agent works best.
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Navigating the Road Ahead: Treatment Strategies Reshaping Multiple Myeloma Care
Nichole Tucker
Meeting News
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March 7, 2025
Do IMID-containing quadruplet therapies represent both the present and future of myeloma treatment?
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Can Teclistamab Address Renal Impairment in Relapsed or Refractory Multiple Myeloma?
Nichole Tucker
Meeting News
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February 21, 2025
A retrospective study supported the safety of teclistamab and demonstrated a PFS benefit for patients with advanced myeloma.
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Zamto-Cel Induces Strong Responses in Relapsed or Refractory DLBCL
Nichole Tucker
Aggressive B-Cell Lymphoma
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February 18, 2025
Results from DALY II USA were presented during the oral abstract session on myeloma and lymphoma at the Tandem TCT Meetings.
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Lacutamab Earns FDA Breakthrough Therapy Designation for Sézary Syndrome Treatment
Nichole Tucker
T-Cell Lymphoma
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February 18, 2025
Based on promising results from the phase II TELLOMAK study, the FDA grants a breakthrough therapy designation for lacutamab.
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Early Referral for Treatment With Axi-Cel Becomes Recommended Standard Approach for Refractory or Relapsed LBCL
Nichole Tucker
Meeting News
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February 18, 2025
Findings from a subgroup analysis of ZUMA-7 support early referral to axi-cel therapy.
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Prolonging Life Without Progression in Large B-Cell Lymphoma: Real-World Insights
Nichole Tucker
Aggressive B-Cell Lymphoma
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February 14, 2025
Real-world data suggest that treatment with either axi-cel or liso-cel provides potential to sustain disease-free survival.
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Linvoseltamab Now Under FDA Review as a Potential Treatment Option for RRMM
Nichole Tucker
Myeloma
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February 11, 2025
Based on LINKER-MM1, FDA approval for linvoseltamab is under consideration.
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Olutasidenib and Azacitidine Combination Expands Options for mIDH1 Relapsed or Refractory AML
Nichole Tucker
Acute Myeloid Leukemia
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February 4, 2025
The first study on the efficacy and safety of an IDH1 inhibitor and hypomethylating agent in advanced AML shows success.
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Pirtobrutinib Delays Progression, Extends Survival in Relapsed or Refractory CLL and SLL
Nichole Tucker
Chronic Myeloid Leukemia
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January 28, 2025
Pirtobrutinib cut disease progression/death risk by 46% vs IdealaR/BR in heavily pretreated relapsed/refractory CLL/SLL.
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Brentuximab Vedotin Combination Shows 37% Reduction in Risk of Death in Relapsed or Refractory DLBCL
Nichole Tucker
Aggressive B-Cell Lymphoma
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January 22, 2025
Adding brentuximab vedotin to lenalidomide and rituximab significantly improved outcomes for patients with R/R DLBCL.
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Zanubrutinib Outperforms Ibrutinib in Delivering Lasting Benefit in Relapsed and Refractory CLL
Nichole Tucker
Chronic Lymphocytic Leukemia
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February 18, 2025
Extended follow-up was conducted for 652 patients with relapsed or refractory CLL or SLL in the ALPINE study.
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FDA Speeds Up Development of Relmacabtagene Autoleucel for Relapsed or Refractory LBCL
Nichole Tucker
Follicular Lymphoma
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January 13, 2025
Relmacabtagene autoleucel is an anti-CD19 chimeric antigen receptor T-cell product
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Debut Study Sparks Hope for siRNA Therapy in Polycythemia Vera
Nichole Tucker
Myeloproliferative Neoplasms
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January 10, 2025
A common treatment goal for polcythemia vera is to control HCT with therapy, phlebotomies, and cytoreductive therapies.
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Five Years In, Axi-Cel Proves Resilience as Relapsed and Refractory iNHL Treatment
Nichole Tucker
Follicular Lymphoma
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January 10, 2025
The 5-year follow-up analysis of ZUMA-5 showed continued efficacy and no new safety signals.
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CAR22 Delivers Breakthrough Results in Small MCL/FL Cohort
Nichole Tucker
Mantle Cell Lymphoma
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January 9, 2025
The phase 1b study of CAR22 is ongoing, and investigators are currently looking to enroll more patients.
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SURPASS-ET Topline Findings Support Broader Label for Ropeginterferon Alfa-2b
Nichole Tucker
Myeloproliferative Neoplasms
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January 13, 2025
SURPASS-ET compared second-line treatment with ropeginterferon alfa-2b with anagrelide in patients with ET.
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RWD Reveal Efficacy Trade-Offs Between Two CAR T-Cell Lymphodepletion Agents for Advanced DLBCL
Nichole Tucker
Aggressive B-Cell Lymphoma
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January 3, 2025
Fludararabine lymphodepletion is more effective than bendamustine lymphodepletion, but more follow-up is needed to confirm.
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Should Intensified Induction Be Part of Frontline Menin Inhibitor Studies in AML?
Nichole Tucker
Acute Myeloid Leukemia
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December 30, 2024
Investigators looked into how intensified induction therapy impacts survival and MRD negativity in patients with AML.
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All-Oral SAVE Regimen Achieves High Rates of Remission in Relapsed or Refractory AML
Nichole Tucker
Acute Myeloid Leukemia
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January 10, 2025
Results from the phase I/II SAVE study in older and unfit patients with relapsed or refractory acute myeloid leukemia.
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